1: Staffed without Western religion (5)
2: Shatters ice cubes (5)
3: Accept amputation to carry on an affair (4,2,3)
4: Weary of ingredients in butterfat, I guess (7)
5: and 19 A Michelangelo masterpiece right over people's heads here? (7,6)
6: Nick's not at church (5)
7: Flooded out and united (9)
8: Charles' equine edges out clown (9)
12: Ice cream containers to Georgia in wagon (9)
13: Strange lingo - some new expression (9)
14: Woman losing head after another fall (9)
16: Journey permitted for one of three babies (7)
17: A rag in question (2,5)
19: Injured after face off and ready to shoot (5)
20: Eskimo intuitions are half-developed (5)
21: Poverty-stricken, longing to rise up and get education (5)