1: Childish nonsense before the last trip (5)
2: Broadway show's inane cast (5)
4: Oil depots destroyed ocean habitats (4,5)
5: Start reorganizing notes (5)
6: Making Athenian weaver drink an informal toast (7,2)
7: Taper rude, non-standard deviation (9)
8: Ermine, missing tail, squeezing into opening in fence to engage in the process of creating new life (9)
13: German award making press cranky (4,5)
14: Every other starlit fish starting search for little percussion instruments (9)
15: Memorandum maintains a balance (9)
16: Formulate a question in mathematical terms (9)
19: Michael Caine, first outspoken host (5)
20: Loud den has style! (5)
21: Church council regulation sounds like a big gun (5)
22: Feeling produced by tease 'n' sex (5)