1: An actress? Direct her in male parts (15)
8: Faced lift-off when stricken (9)
9: Don't accept deterioration (7)
10: Agree to make Lucifer wicked? (3)
12: Begins seeing another divorcee? Deplorable. (3)
14: Lies for each twelve men (7)
15: Either way, it's flat (5)
16: Lion's leader publicizes dens (5)
17: Language - one with a Latin derivation (7)
18: Pious woman in underground hideaway (3)
19: Lifeblood of dope (3)
20: Black hole shows how droppings take time (7)
21: Where one may play an instrument as a novice (9)
22: Risk solemn query about primates (8,7)